Open an existing CellML file from a local directory or the Physiome Model Repository

Go to the File menu and select Open… (File ‣ Open). Browse to the folder that contains your existing models and select one. Note that this brings up a new tabbed window and you can have any number of CellML models open at the same time in order to quickly move between them. A model can be removed from this list by clicking on next to the CellML model name.

You can also access models from the left hand panel in Fig. 1(a). If this panel is not currently visible, use ‘CTRL-spacebar’ to make it reappear. Models can then be accessed from any one of the three subdivisions of this panel – File Browser, Physiome Model Repository or File Organiser. For a file under File Browser or File Organiser, either double-click it or ‘drag&drop’ it over the central workspace to open that model. Clicking on a model in the Physiome Model Repository (PMR) (e.g. Chen, Popel, 2007) opens a new browser window with that model (PMR is covered in more detail in Section 13). You can either load this model directly into OpenCOR or create an identical copy (clone) of the model in your local directory. Note that PMR contains workspaces and exposures. Workspaces are online environments for the collaborative development of models (e.g. by geographically dispersed groups) and can have password protected access. Exposures are workspaces that are exposed for public view and mostly contain models from peer-reviewed journal publications. There are about 600 exposures based on journal papers and covering many areas of cell processes and other ODE/algebraic models, but these are currently being supplemented with reusable protein-based models – see discussion in a Section 13.

To load a model directly into OpenCOR, click on the right-most of the two buttons in Fig. 5 - this lists the CellML models in that exposure - and then click on the model you want. Clicking on the left hand button copies the PMR workspace to a local directory that you specify. This is useful if you want to use that model as a template for a new one you are creating.

Fig. 5 The Physiome Model Repository (PMR) window listing all PMR models. These can be opened from within OpenCOR using the two buttons to the right of a model, as explained below.

In the PMR window (Fig. 5) the buttons on the right-hand side [1] lists all the CellML files for this model. Clicking on one of those [2] uploads the model into OpenCOR. The left-hand buttons [3] copies the PMR workspace to a local directory.